Description
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. PELI1 may function to control inadvertent activation of RIP3, thus preventing aberrant cell death and maintaining cellular homeostasis. PELI1 might participate in B-cell maturation or oncogenic activation of aggressive B-cell lymphomas, both during and after germinal center stages.
This Human Pellino-1 overexpression lysate was created in Baculovirus-Insect Cells and intented for use as a Western blot (WB) positive control. Purification of Pellino-1 protein from the overexpression lysate was verified